Showing posts with label pharmaceutical firms. Show all posts
Showing posts with label pharmaceutical firms. Show all posts

Wednesday, April 1, 2015

Biotech Firm Shows San Diego How New Products Draw Investment



San Diego’s has added another successful business to its budding biotech hub. Start-up firm aTyr Pharma, Inc. drew over $76 million investment capital from Sofinnova Ventures and another undisclosed entity to develop its drug called Resolaris that helps treat muscular dystrophy (Fikes, 2015). Biotech firms like aTyr help encourage greater investment and employment in the San Diego economy.

Every investment opportunity comes with risk and rewards. Venture capitalists diligently assess whether the risks and rewards are worth investing their hard earned capital.  Risk tolerant investors are more likely to get involved in highly innovative startups (Tian & Wang, 2014). In this case, a single patentable and profitable drug can make or break the firm’s long-term future.  

The ability to have exclusive rights to manufacture an important drug can be worth hundreds of millions of dollars. Approval of Resolaris for use and testing in the E.U., U.S. and other markets will add significantly to its value. The risks are lower and potential profit higher for companies that already have approvals.

Cities like San Diego have growing biotech hubs that produce more pharmaceutical start-ups than cities with less developed networks. The knowledge needed to invent and produce new drugs come from clusters of like-minded individuals who work within the local pharmaceutical industry. As they act and interact they innovate new drugs, models, and products.

When new start-ups develop they will draw more investors to the area seeking better opportunities to expand their investment portfolios. Successful start ups rely on existing local knowledge learned from communities that encourage an entrepreneurial spirit. As start ups make their way out of the incubation periods and product tangible products investors flock in maximize profits both helping local businesses as well as expanding employment opportunities.

Fickes, B. (April 1st, 2015). San Diego biotech raises $76 million. UT San Diego. Retrieved http://www.utsandiego.com/news/2015/apr/01/atyr-76-million-financing/

Tian, X. & Wang, T. (2014). Tolerance for failure and corporate innovation. Review of Financial Studies, 27 (1).

Thursday, February 14, 2013

Innovative Companies Localized into Regional Hubs


Innovation is becoming a concept that nations hope to foster as their financial situations become more dire. Research in national innovation helps to highlight how the concepts of regional hubs can help further this development by creating hives of innovative knowledge sharing. Companies don’t work within isolation and often share knowledge, people, and ideas throughout a region. Research into the development of the pharmaceutical industry furthers this concept of demographic influence.

Innovation is a necessary component of organizational growth and development. Theoretical and empirical literature helps establish an understanding that innovation responds to consumer demand (Schmookler, 1966). In other words, that as customers have needs they desire to be fulfilled, organizations will often develop products and services to meet those needs. The stronger the feedback loop the more likely such customer to company interaction will lead to new innovative insights.

All innovation requires knowledge. This knowledge comes from past experiences, sharing information, new research, education, market needs, and communication. The knowledge that is derived from market and consumer demand and is often difficult to codify in concise terms that can be applied appropriately (Polanyi, 1966). Without strong analysis and customer research it is difficult to determine what consumers are looking for in order to develop these new products and services.

This difficulty in codifying needs into concise terms means that such understandings often are derived from multiple pathways as a result of local communication. It seeps into the organizations in an amebic fashion. Those firms that operate on a local level have a better understanding of the tacit needs of their customers (Kogut, 1993). It is through constant communication with customers and the local market that such needs and solutions finally become crystallized. 

In innovation there is also a pull and push strategy in much the same manner as there is in marketing. Demand pull from the market helps to shape innovative investments (Schmookler, 1966). As customers create needs, organizations will naturally respond to those needs. Furthermore, there is also technology push that comes from the science, learning, research, knowledge, manufacturing and production. Such inventions create a frontier by which new products and services can create markets (Griliches, 1995).

To see how this push and pull strategy, combined with local knowledge, creates innovation it is possible to look at those cities and counties that have a disproportionate amount of new market offerings. Technology organizations create a spillover influence in their regions that offers an opportunity for shared development (Feldman, 2000). In essence, the transferring of people, information, culture, and knowledge among a hub of businesses creates innovative synergy in the area. 

The research conducted by Fabrizio & Thomas (2012) helps solidify this understanding of innovative locality. The research used a panel dataset of new molecule innovation from the 56 largest pharmaceutical firms in nine different countries between 1992 and 2001. The study focused on analysis of the parent and sub-firms that reside in local markets even though they have international presence for their products. They reviewed 1,085 new market offerings from 1980 to 2001 trying to canvas innovation within the industry. They analyzed these findings with technology data and local information to come to a pattern of innovative development.

Results:

-Accumulated technical knowledge by measuring organizations patents determines innovation.

-Knowledge of the market also determines the pattern of innovations created. 

-Systems of organizations, culture, and similarity of industries in local regions impact innovation.

-The use of open innovation, networks, and knowledge sharing processes encourages innovation.

-There are no international pharmaceutical innovations only national ones that make their products available on the international markets.

-The local and national culture has an impact on the likelihood of innovation.

-It is recommended that innovative organizations establish themselves with the local market to understand consumer needs and develop new products.

The results shed light on the overall development of innovation within nations. Organizations that are innovative work best when located in a hub of like companies. The knowledge sharing among market members furthers the development of new ideas and concepts. Nations can foster this innovative process by developing such hubs similar to technology organizations in Silicon Valley or automotive manufacturing in the Detroit area. Furthermore, the national and regional culture also impacts the success of developing new innovative products for global market presence.

Fabrizio, K. & Thomas, L. (2012). The impact of local demand on innovation in a global industry. Strategic Management Journal, 33.

Feldman MP. (2000). Location and innovation: the new economic geography of innovation, spillovers, and agglomeration. In Oxford Handbook of Economic Geography, Clark G, Feldman M, Gertler M (eds). Oxford University Press: Oxford, UK; 373–394.

Griliches Z. 1995. R&D and productivity: econometric results and measurement issues. In Handbook of the Economics of Innovation and Technological Change, Stoneman P (ed). Blackwell: Oxford, UK; 52–89.

Kogut B. 1993. Country Competitiveness: Technology and the Organizing of Work . Oxford University Press: New York.

Polanyi M. 1966. The Tacit Dimension. Doubleday: Garden City, NY.

Schmookler J. 1966. Invention and Economic Growth Development. Harvard University Press: Cambridge, MA.
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